Bullseye on Breast Cancer!

http://www.telegraph.co.uk/earth/main.jhtml?view=DETAILS&grid=&xml=/earth/2008/03/12/scicanc112.xml

Breast cancer 'master gene' breakthrough

By Roger Highfield, Science Editor

Last Updated: 6:01pm GMT 12/03/2008

Thousands of women who suffer from breast cancer were
today given fresh hope after scientists announced they had
discovered a way to stop the disease spreading.

Researchers find breast cancer trigger Scraps stop breast cancer in its tracks Aspirin 'can cut breast cancer risk by 20pc' The breakthrough paves the way for the development of drugs which could halt the progress of the disease and help save the lives of some of the 44,000 women diagnosed with the illness every year. SATB1 forms a 3D cage-like structure within the cell nucleus (left) that binds to DNA specific sites in genes The most deadly feature of breast cancer is when it disperses from the breast, causing tumours to develop in other parts of the body. But now researchers say they have found a way of stopping this process, known as metastasis, after pinpointing the gene which controls the spread of the cancer. By removing this gene from cancer cells the American teams of scientists were able to halt its progress and even turned the cancer cell back to normal. The gene, called SATB1, is thought to control the use of around 1000 others to promote the spread, says Dr Terumi Kohwi-Shigematsu of the Lawrence Berkeley National Laboratory, California, whose r esearch is published in the journal Nature today.

Simply Awesome!